Arimidex

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Arimidex® (anastrozole) is a prescription medication used in the treatment of certain types of breast cancer in postmenopausal women. The drug is taken orally once a day, and can be used on its own or with other treatments, including surgery and radiation.

Arimidex® is a nonsteroidal aromatase inhibitor that lowers the amount of certain estrogens in the body. This can, in turn, slow down or stop the growth of certain breast cancer cells that use estrogen to grow.[1]

Side effects of Arimidex® range from mild reactions like headache and constipation to severe symptoms like chest pain, skin lesions, pain, and jaundice.[1]


Arimidex.jpg
Flickr: shutterbugmuse
Brand name for Anastrozole
Manufacturer AstraZeneca[2]
Uses Treatment of certain types of breast cancer in postmenopausal women[2]
Common side effects Hot flashes, headache, weakness, nausea, diarrhea, vomiting, etc.[1]
Major side effects Hives, rash, blurred vision, chest pain, sore throat, swelling of eyes, face, throat, lips, arms, hands, ankles, feet, lower legs, etc.[1]
Warnings May cause or worsen osteoporosis[1]
Disclaimer The information provided by PharmacyDrugGuide.com is not a substitute for professional medical advice, diagnosis, or treatment. Do not take any action based on the information on this page without consulting a physician.
Author Allison Hughes
 
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Contents

About Arimidex

Arimidex® is the brand name for the drug anastrozole, and is approved by the FDA for the treatment of several types of breast cancer in postmenopausal women. The medication is primarily used for hormone receptor-positive early breast cancer, but is approved for other breast cancers as well. This includes, but is not limited to the following:[3]

  • First breast cancer treatment for postmenopausal women whose cancer has already spread within the breast or to other areas of the body.
  • Treatment of breast cancer in postmenopausal women whose cancer has worsened after taking the drug tamoxifen.
  • Breast cancer prevention for women at high risk of developing the illness.

Manufactured by the pharmaceutical company AstraZeneca, Arimidex® was first approved for treatment of advanced breast cancer in 1995, and early breast cancer treatment in 2002. It is approved for use after surgery, and may be used in conjunction with radiation therapy. Arimidex® treatment is usually administered to patients for several years.[1]

Prescription Drugs

Basic information about prescription drugs like Arimidex
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Arimidex Side Effects

Arimidex® may cause side effects, some of them serious. Common side effects include, but are not limited to the following:[1]

  • Hot flashes
  • Weakness
  • Mood changes
  • Joint, bone or muscle pain
  • Nausea
  • Headache
  • Diarrhea

More dangerous adverse reactions, requiring medical observation, include:[1]

  • Changes in vision, like blurriness
  • Pain in the chest
  • Pain in the upper right portion of the stomach
  • Painful urination, trouble urinating, or the urgent need to urinate
  • Flushing or swelling in the arms or hands
  • Signs if flu, like sore throat, high temperature and chills

Arimidex Clinical Trial

Arimidex® was part of one of the largest clinical trials for the treatment of early breast cancer in postmenopausal women. The ATAC study took place over an 8-year period, and followed women during five years of treatment on the drug(s) and 3-years of follow-up. The ATAC study, which stands for Arimidex®, Tamoxifen Alone or in Combination, examined the treatment of postmenopausal women with early breast cancer that were prescribed Arimidex®, Taxmoxifen®, or both.[4]


Arimidex Abuse

Arimidex® is typically not an abused drug, as it does not produce any psychological or euphoric effects and it is not a stimulant. However, any drug may be abused if it is taken for reasons other than prescribed. Abusing prescription drugs can be dangerous or even deadly, and Arimidex® should not be taken without a doctor's prescription.[5]

Treating Breast Cancer

Breast cancer can occur in both males and females, although it is far more likely to affect women. It is characterized by growth of cancerous cells in breast tissue, and typically starts out in milk glands and ducts.[6]

Breast cancer is treated in a number of ways. Typically, surgery is performed to remove the cancerous tissue. Sometimes only the tumor itself is removed, while in other cases it is necessary to remove some or all of the breast. Other treatments include radiation therapy, chemotherapy, hormonal treatment and medications such as Arimidex®. Some breast cancer patients may opt to participate in clinical trials to test out new medicines and other types of treatments.[7]

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Also See: Arimidex Coupons, Arimidex Free Samples, Arimidex Patient Assistance Programs, Arimidex Side Effects, Avastin Side Effects, Breast Cancer Awareness Month, Avastin Side Effects, Femara Side Effects

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References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 http://www.nlm.nih.gov/medlineplus/druginfo/meds/a696018.html
  2. 2.0 2.1 http://www.arimidex.com/
  3. http://www.arimidex.com/about-arimidex.aspx
  4. http://www.arimidex.com/clinical-trial-results.aspx#a1
  5. http://www.nlm.nih.gov/medlineplus/prescriptiondrugabuse.html
  6. http://www.cancer.gov/cancertopics/types/breast
  7. http://www.cancer.gov/cancertopics/pdq/treatment/breast/Patient/page5