Celebrex Side Effects

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Celebrex is the brand name for celecoxib, a prescription non-steroidal anti-inflammatory drug, or NSAID, used to treat arthritis, arthritic pain, and inflammation. The drug is prescribed for patients with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.[1]

Celebrex® is a Pfizer, Inc. medication that was first approved by the FDA in 1998. It is available in 50 mg, 100 mg, 200 mg, and 400 mg capsules, and is taken once or twice daily, with or without food.[1] Common side effects caused by Celebrex® may include headaches, dizziness, gas, and upset stomach. Serious reactions such as ulcers and intestinal bleeding can also occur.[2]

Flickr: ccox888
Brand name for Celecoxib
Manufacturer Pfizer, Inc.
Uses Treatment of the symptoms of Rheumatoid arthritis, Osteoarthritis, acute pain in adults, and signs and symptoms of Ankylosing Spondylitus[3]
Common side effects Gas, diarrhea, cold-like symptoms[4]
Who should not take Celebrex® Patients allergic to celecoxib, other NSAIDs, sulfonamides drugs, and aspirin or patients who have had coronary artery bypass graft surgery[5] [4]
Disclaimer The information provided by PharmacyDrugGuide.com is not a substitute for professional medical advice, diagnosis, or treatment. Do not take any action based on the information on this page without consulting a physician.
Author Allison Hughes


Common Celebrex Side Effects

In clinical trials, the most common adverse reaction, occurring in 15.8 percent of the patients, was headache. Upper respiratory infections and dyspepsia occurred in more than 8 percent of participants, while more than 5 percent experienced diarrhea and sinusitis. [1] More serious side effects that may require emergency medical help include:[4]

  • Difficulty urinating
  • Cloudy or discolored urine
  • Jaundice
  • Problems breathing
  • Difficulty swallowing
  • Signs of the flu

About Medication Side Effects

Common possible side effects of prescription and nonprescription drugs

Celebrex Allergic Reactions

Celebrix® can cause severe allergies on the skin or internally. In some cases, these allergies can be life-threatening. Users are advised by the manufacturer to seek immediate medical help if swelling in the facial area or the throat occurs, or if there are any problems with respiration. Patients who are allergic to celecoxib, other NSAIDs, aspirin, or drugs called sulfonamides are likely to experience reactions to Celebrex®.[6]

Celebrex Precautions and Warnings

  • Patients taking low-dose aspirin for their heart may be at an increased risk for stomach bleeding and ulcers.[3] Patients taking any NASIAD may be at an increased risk of experiencing gastrointestinal problems, especially in patients who have had gastrointestinal bleeding or ulcer diseases previously.[1]
  • Celebrex® can cause fetal harm, particularly when taken in the early or later phases of pregnancy.[6]
  • Patients who take Celebrex® and other NSAIDs are at an increased risk of cardiovascular problems. This risk is increased in patients who have high blood pressure.[6]
  • The manufacturer warns patients not to take Celebrex® right after or right before they undergo heart surgery.[6]
  • The National Institutes of Health warns patients not to take Celebrex® if they have experienced an allergic reaction to aspirin or other NASIDs in the form of hives or an asthma attack.[1]

Understanding Arthritis

Arthritis is an inflammation of the joints that may occur in one or more areas of the body. The disease tends to progress with age, and causes pain and stiffness. Some arthritis, known as osteoarthritis, is the direct result of joint usage over time. Another kind, rheumatoid arthritis, is a result of autoimmune disorder. These are the most widespread types of arthritis, although there are several other less common ones as well.[7]

Treatment options typically include physical therapy, drugs, and surgery. Overweight patients are advised to lose weight in order to ease pressure on the joints, and exercise is also recommended to boost flexibility in the joints.[7]


Also See: Drug Side Effects, Celebrex Free Samples, Celebrex Coupons, Celebrex Patient Assistance Programs, Orencia Side Effects


  1. 1.0 1.1 1.2 1.3 1.4 http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=11083
  2. http://www.celebrex.com/default.aspx
  3. 3.0 3.1 http://www.celebrex.com/IsCELEBREXRightforYou.aspx
  4. 4.0 4.1 4.2 http://www.nlm.nih.gov/medlineplus/druginfo/meds/a699022.html
  5. http://www.pfizerpro.com/products?product=/wyeth_html/home/products/prescription/celebrex/patient-resources.html
  6. 6.0 6.1 6.2 6.3 http://www.celebrex.com/safety-info.aspx
  7. 7.0 7.1 http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002223/