Plavix Side Effects

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Plavix® (clopidogrel) is a prescription medication designed to reduce the risk of blood clotting by keeping platelets from sticking together. Classified as an antiplatelet drug, Plavix® can reduce the risk of having a heart attack or stroke. Plavix® it is manufactured by Bristol Myers Squibb in partnership with Sanofi.[1]

The drug has been highly researched and can effectively protect patients from serious cardiovascular events, but there are numerous side effects associated with Plavix®. Common adverse reactions include nosebleeds, drowsiness, headache, and upset stomach. In serious cases, severe bleeding can occur. Plavix® does not work well with everyone, and genetic factors can decrease the drug's effectiveness.[2]

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Brand name for Clopidogrel
Manufacturer Bristol-Myers Squibb and Sanofi[1]
Uses Reduce the risk of blood clots, helping to prevent heart attack and stroke[1]
Common side effects Sinus infection, indigestion, backache, head pain, stomach cramps, skin discoloration, chest pain, dizziness, etc.[1]
Who should not take Plavix®? Individuals with conditions that cause a bleeding ulcer, those unable to properly metabolize the drug[1]
Disclaimer The information provided by is not a substitute for professional medical advice, diagnosis, or treatment. Do not take any action based on the information on this page without consulting a physician.
Author Laura Acevedo


Common Plavix Side Effects

The most common adverse reaction among Plavix® users is increased bleeding. In some instances, this bleeding can be life-threatening.[1]

Other common side effects can include chest pain, sinus infections, stomach cramps, dizziness, joint pain, flu-like symptoms, brown or purple skin blotches, head pain, indigestion and backaches.[1]

Some less common side effects of Plavix® include high blood pressure, urinary track infections, bronchitis, bleeding in the stomach or intestines, cataracts, difficulty breathing, gout, diarrhea, cough, eczema, depression, leg cramps, difficulty sleeping, anxiety, nausea, numbness, low energy and anemia.[1]


Plavix Allergic Reactions

While allergic reaction is not a common issue with Plavix®, any problems with breathing, a rash, or other allergic symptoms may indicate a severe reaction and are cause to seek immediate medical attention. Users may be allergic to clopidorgel, or to the inactive ingredients of Plavix®. These include polyethylene glycol 6000, hydrogenated castor oil, microcrystalline cellulose, hydroxypropylcellulose, and manitol.[1]

Plavix Coupons

Ways patients can save money on Plavix prescriptions

Plavix Precautions and Warnings

  • Plavix® may not be effective for patients taking other prescriptions, such as Prilosec®.[1]
  • Individuals who already have an ulcer, or have a condition that makes them prone to bleeding ulcers, are advised not to take Plavix® as dangerous bleeding may occur.[1]
  • Those with recent injuries may be at risk of severe bleeding if they take Plavix®.[2]
  • Patients with liver or kidney disease may not be right for Plavix®.[2]
  • Patients are advised to seek medical attention if they experience dark, tarry stools; blood in the urine; blood or blood clots that come up while coughing; blood or a dark, granular substance in vomit; or bruises that cannot be explained or grow in size. These can indicate excessive bleeding, which can be deadly if left untreated.[2]
  • Patients who need any type of surgery, including dental surgery, are instructed to inform their physicians of Plavix® use.[2]
  • Patients will likely need to undergo lab tests to see if their bodies turn Plavix® into its active form. Depending on test results, other forms of treatment may be pursued instead of Plavix®.[2]


Also See: Plavix, Plavix Patient Assistance Programs, Plavix Free Samples, Plavix Coupons, Drug Coupons, Aspirin Coupons, Zocor Coupons, Diovan Free Samples, Lipitor Coupons



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