From Pharmacy Drug Guide
Zoloft® (sertraline) is a prescription antidepressant in a class known as selective serotonin reuptake inhibitors (SSRIs). SSRIs work by increasing the amount of serotonin in the brain. Zoloft® is approved by the FDA for the treatment of major depression, obsessive-compulsive disorder, panic attacks, posttraumatic stress disorder, social anxiety disorder, and premenstrual dysphoric disorder.
Side effects of Zoloft® include dryness in the mouth, reduced appetite, nausea, sexual dysfunction, insomnia and diarrhea. In severe cases, Zoloft® can cause uncontrollable shaking and extreme mood changes including suicidal thoughts or tendencies. Suicide attempts or ideologies with Zoloft® are most common among patients under the age of 24.
|Brand name for||Sertraline|
|Uses||Major depressive disorder (MDD), obsessive-compulsive disorder (OCD), panic disorder, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), social anxiety disorder|
|Common side effects||Nausea, diarrhea, constipation, vomiting, dry mouth, gas or bloating, loss of appetite or weight changes, drowsiness, dizziness, excessive tiredness, nervousness, changes in sex drive or ability|
|Major side effects||Vision changes, seizures, fever, confusion, fast or irregular heartbeat, abnormal bleeding or bruising, hallucinations|
|Warnings||Patients who have recently had a heart attack, seizures or liver or heart disease, or who are allergic to latex (for oral solution) may be unable to take Zoloft®. Patients taking monoamine oxidase inhibitors (MAOI), pimozide (Orap), or disulfiram (Antabuse) cannot take Zoloft®. A small number of children, teenagers, and young adults experience suicidal thoughts while taking Zoloft®.|
|Disclaimer||The information provided by PharmacyDrugGuide.com is not a substitute for professional medical advice, diagnosis, or treatment. Do not take any action based on the information on this page without consulting a physician.|
Zoloft® is an antidepressant used to treat several different disorders:
- Major depression, a mood disorder in which feelings like sadness or loss interfere with everyday life for a long period of time.
- Obsessive-compulsive disorder, characterized by troublesome thoughts that persist, and the need to repeat specific actions.
- Panic disorder, in which patients experience recurrent panic attacks and may or may not suffer from agoraphobia, a fear of settings like crowds, bridges and the outdoors.
- Posttraumatic stress disorder, a condition developed after a particularly traumatic or frightening event that may involve actual or threatened death or serious injury. 
- Social anxiety, an extreme fear of interacting with other people that hinders normal life. 
- Premenstrual dysphoric disorder, which includes mood swings, irritability, bloating, and breast tenderness. 
Zoloft® is not a controlled substance and it is not commonly abused. While therapeutic doses do result in positive mood changes, large doses or doses taken by alternate methods do not seem to produce a desired effect. Zoloft® overdose may result in somnolence (drowsiness), vomiting, fast heart rate, nausea, dizziness, agitation, tremor, and death.
Zoloft® Side Effects
Zoloft® has a number of common side effects. These may include:
- Nausea or vomiting
- Gas or bloating
- Loss of appetite or weight changes
- Drowsiness or excessive tiredness
- Pain, burning, or tingling in the hands or feet
- Changes in sex drive or ability
- Excessive sweating
Major side effects of Zoloft® are rare, but may require medical assistance:
- Swelling of the face, throat, or tongue
- Difficulty breathing
- Vision changes
- Fast or irregular heartbeat
- Severe muscle stiffness
- Abnormal bleeding or bruising
- Zoloft® can cause complications if used in the final stages of pregnancy.
- Due to the possibility of drowsiness, Zoloft® patients are cautioned against operating a motor vehicle until it is clearly safe to do so on the medication.